Excessive-Throughput Platform Reduces Handbook Steps by as much as 90%.
Picture Credit score: Beckman Coulter Life Sciences
Beckman Coulter Life Sciences, a world chief in laboratory automation and innovation, and an organization of Danaher Company (NYSE: DHR), launches the Cydem VT Automated Clone Screening System, a revolutionary high-throughput microbioreactor platform for automated prime clone screening.
The brand new Cydem VT System considerably reduces time to marketplace for biologic drug discovery and monoclonal antibody-based therapeutics, by slashing guide laboratory steps in Cell Line Improvement as much as 90% in a single experiment, and eliminating the necessity for a lot of subsequent conventional screening steps.
By delivering early solutions for cell development and productiveness within the cell line growth course of, the Cydem VT System supplies labs with extra dependable clones in comparison with conventional strategies, together with higher cultivation circumstances which can be nearer to biomanufacturing manufacturing. The all-in-one high-throughput screening platform is right in cell line growth of Chinese language Hamster Ovary (CHO) cell traces producing monoclonal antibodies (mAbs).
“Our Cydem VT Automated Clone Screening System presents an thrilling revolution to expedite crucial analysis therapies for diseases, together with autoimmune ailments and plenty of varieties of most cancers,” mentioned Product Supervisor Dr. Sebastian Hofzumahaus. “We heard the issues about deciding on poor productiveness clones and understood the crucial have to develop an easy-to-use answer that confidently and constantly identifies the very best clones. By means of offering early solutions and higher cultivation circumstances, we’re in a position to make sure higher accuracy with fewer steps to cut back the chance of dangerous clones to assist laboratories uncover their subsequent massive breakthrough even quicker and positively influence human well being.”
The system combines a number of trusted Beckman Coulter Life Sciences applied sciences together with microbioreactor, liquid dealing with, antibody titer and cell well being (cell depend & viability) measurements into one superior platform that empowers lab managers with a simpler, higher-throughput technique for prime clone screening. It permits parallel pH-controlled, fed-batch cultivation and monitoring of as much as 96 bioreactors with particular person gassing.
Automated operations present at the least three days of walk-away time throughout an experiment. On-line, non-invasive pH, dissolved oxygen (DO) and biomass measurements present steady management over crucial cultivation parameters. On-deck willpower of cell focus, viability and titer focus guarantee knowledgeable choice of the highest clones. Be taught extra concerning the Cydem VT Automated Clone Screening System by clicking right here.
About Beckman Coulter Life Sciences
With a relentless mission to empower these looking for solutions to life’s essential scientific questions, Beckman Coulter Life Sciences is a most well-liked laboratory accomplice offering automation and innovation options for Centrifugation, Circulation Cytometry, Genomics, Particle Evaluation, and Liquid Dealing with workflows. With a legacy relationship again to 1935, our applied sciences cut back guide laboratory processes and may present higher pace, accuracy, and superior analytics to speed up solutions with a guiding focus to enhance affected person care and allow pioneering discoveries. Beckman Coulter Life Sciences, a part of the Danaher Company (NYSE: DHR) household of worldwide science and know-how firms, is headquartered in Indianapolis, Indiana with 11 operational hubs around the globe and employs roughly 2,800 associates with greater than 400,000 methods put in globally. Get to know us by clicking right here and by following us on LinkedIn.
Product not to be used in diagnostic or therapeutic procedures. Product in growth. Efficiency traits haven’t been validated.
