Interviewee: Dr. Justin Matheson, | Authors/Editors: Romina Garcia de leon, Janielle Richards (Weblog Co-coordinators)
Printed: September sixth, 2024
Are you able to briefly clarify your analysis?
My analysis focuses on understanding how intercourse and gender form substance use well being, which encompasses the continuum from preliminary drug use experiences to substance use problems. Particularly, in my present analysis, I’m concentrating on two essential areas. The primary is analyzing variations in acute responses to hashish utilizing a human behavioral pharmacology paradigm. On this paradigm, contributors smoke hashish within the lab, and we observe categorical variations of their responses, equivalent to how excessive they really feel and their cognitive and typically driving efficiency. The second focus is on how gender influences trajectories and experiences in hashish use dysfunction therapy, together with the sort and severity of signs skilled by people present process therapy to scale back or cease hashish use. The goal is to raised perceive these trajectories, significantly in cisgender girls and gender minorities, and to enhance prevention and therapy methods for substance use problems, particularly hashish use problems.
How did you get into this analysis?
I sort of stumbled into this discipline when, as a PhD pupil, my supervisor steered that we discover variations in our preliminary hashish lab examine for a convention presentation. As I reviewed the literature, I turned more and more conscious of how a lot hurt in science has been attributable to andronormativity, the deal with males and male our bodies. Substance use has usually been framed as a “males’s subject,” and habit in girls is much less understood, with restricted analysis on habit in gender minorities. As a gender-fluid individual, I felt it was essential to work in the direction of gendered well being fairness within the habit discipline inside a restorative social justice framework, addressing gaps in understanding how substance use impacts cisgender girls and gender minorities.
How do you outline intercourse and gender in your work?
Initially, my method was to make use of a basic categorical distinction mannequin—males versus females. Nevertheless, I’m now shifting in the direction of exploring the underlying components driving these categorical variations. For instance, I’m within the relationship between gonadal hormone ranges and acute responses to medicine, and the way these relationships differ with the menstrual cycle or menopause. There’s a important lack of empirical proof on how menopause would possibly affect habit threat. Whereas my analysis remains to be grounded in binary classes, I goal to maneuver past this binary to look at related components that have an effect on all our bodies in another way based mostly on gender. I consider gender as a approach of creating which means of our bodies and the way societal understandings of gender affect how people are handled. Traditionally, substance use has been extra stigmatized for ladies, contributing to underreporting and fewer focus in analysis. Girls with hashish use problems usually face extra interpersonal conflicts, whereas males could expertise extra neurobiological or pharmacological hurt. My analysis seeks to know how gender and biology work together and the way these interactions affect substance use and habit.
Are there any findings you would share with us?
In our human laboratory work, we’ve encountered challenges. For instance, in my preliminary PhD analysis, feminine contributors smoked much less hashish than males and had decrease THC ranges of their blood than anticipated. Regardless of reporting comparable subjective and cognitive results as males, the distinction in blood THC ranges was important. Nevertheless, subsequent makes an attempt to copy this discovering have been inconclusive. We’re exploring how contextual components (e.g., temper, expectations, prior hashish use historical past) would possibly reasonable the connection between THC publicity and intoxication states. We’re additionally investigating the affect of menstrual cycle part, estrogens, and androgens on hashish use. In our gender-related analysis, which is primarily qualitative, we’ve recognized notable gender narratives. For example, males usually search therapy after struggling to chop again on hashish, whereas girls regularly cite exterior pressures and disgrace associated to their hashish use. These preliminary findings counsel a necessity for additional exploration of how gender influences treatment-seeking behaviors and limitations to accessing care.
The place do you hope to see this work in 10 years?
Within the subsequent decade, I hope to safe extra funding for analysis on particular components associated to substance use. There’s a important hole in understanding how menstrual cycle phases affect hashish use, with just one printed examine on this space. I goal to fill this hole and discover neuroendocrinological approaches, together with hormone modeling and genetic components. Moreover, I hope to combine gender extra systematically into laboratory research, transferring past qualitative analysis to develop quantitative measures of gender. For instance, understanding how people who establish as extra female could expertise hashish intoxication in another way could possibly be essential. In the end, I goal to merge analysis on gender and hashish use dysfunction with research on particular person variations in drug responses, to enhance prevention and therapy methods for hashish use problems and different substance use problems.
The place are you able to study extra about Dr. Justin Matheson’s work?
Web site: https://www.justinrmatheson.com/
Twitter/X: https://x.com/justinrmatheson
