Interviewee: Dr. Justin Matheson, | Authors/Editors: Romina Garcia de leon, Janielle Richards (Weblog Co-coordinators)
Revealed: September sixth, 2024
Are you able to briefly clarify your analysis?
My analysis focuses on understanding how intercourse and gender form substance use well being, which encompasses the continuum from preliminary drug use experiences to substance use problems. Particularly, in my present analysis, I’m concentrating on two fundamental areas. The primary is inspecting variations in acute responses to hashish utilizing a human behavioral pharmacology paradigm. On this paradigm, members smoke hashish within the lab, and we observe categorical variations of their responses, akin to how excessive they really feel and their cognitive and generally driving efficiency. The second focus is on how gender influences trajectories and experiences in hashish use dysfunction therapy, together with the sort and severity of signs skilled by people present process therapy to scale back or cease hashish use. The purpose is to higher perceive these trajectories, significantly in cisgender ladies and gender minorities, and to enhance prevention and therapy methods for substance use problems, particularly hashish use problems.
How did you get into this analysis?
I form of stumbled into this area when, as a PhD scholar, my supervisor advised that we discover variations in our preliminary hashish lab research for a convention presentation. As I reviewed the literature, I turned more and more conscious of how a lot hurt in science has been brought on by andronormativity, the deal with males and male our bodies. Substance use has usually been framed as a “males’s concern,” and dependancy in ladies is much less understood, with restricted analysis on dependancy in gender minorities. As a gender-fluid particular person, I felt it was necessary to work in the direction of gendered well being fairness within the dependancy area inside a restorative social justice framework, addressing gaps in understanding how substance use impacts cisgender ladies and gender minorities.
How do you outline intercourse and gender in your work?
Initially, my strategy was to make use of a traditional categorical distinction mannequin—males versus females. Nonetheless, I’m now shifting in the direction of exploring the underlying elements driving these categorical variations. For instance, I’m within the relationship between gonadal hormone ranges and acute responses to medication, and the way these relationships range with the menstrual cycle or menopause. There’s a vital lack of empirical proof on how menopause would possibly impression dependancy danger. Whereas my analysis continues to be grounded in binary classes, I purpose to maneuver past this binary to look at related elements that have an effect on all our bodies in a different way primarily based on gender. I consider gender as a manner of constructing that means of our bodies and the way societal understandings of gender affect how people are handled. Traditionally, substance use has been extra stigmatized for ladies, contributing to underreporting and fewer focus in analysis. Girls with hashish use problems usually face extra interpersonal conflicts, whereas males might expertise extra neurobiological or pharmacological hurt. My analysis seeks to know how gender and biology work together and the way these interactions affect substance use and dependancy.
Are there any findings you could possibly share with us?
In our human laboratory work, we’ve encountered challenges. For instance, in my preliminary PhD analysis, feminine members smoked much less hashish than males and had decrease THC ranges of their blood than anticipated. Regardless of reporting related subjective and cognitive results as males, the distinction in blood THC ranges was vital. Nonetheless, subsequent makes an attempt to duplicate this discovering have been inconclusive. We’re exploring how contextual elements (e.g., temper, expectations, prior hashish use historical past) would possibly average the connection between THC publicity and intoxication states. We’re additionally investigating the impression of menstrual cycle part, estrogens, and androgens on hashish use. In our gender-related analysis, which is primarily qualitative, we’ve recognized notable gender narratives. For example, males usually search therapy after struggling to chop again on hashish, whereas ladies incessantly cite exterior pressures and disgrace associated to their hashish use. These preliminary findings recommend a necessity for additional exploration of how gender influences treatment-seeking behaviors and obstacles to accessing care.
The place do you hope to see this work in 10 years?
Within the subsequent decade, I hope to safe extra funding for analysis on particular elements associated to substance use. There’s a vital hole in understanding how menstrual cycle phases impression hashish use, with just one revealed research on this space. I purpose to fill this hole and discover neuroendocrinological approaches, together with hormone modeling and genetic elements. Moreover, I hope to combine gender extra systematically into laboratory research, shifting past qualitative analysis to develop quantitative measures of gender. For instance, understanding how people who determine as extra female might expertise hashish intoxication in a different way may very well be essential. In the end, I purpose to merge analysis on gender and hashish use dysfunction with research on particular person variations in drug responses, to enhance prevention and therapy methods for hashish use problems and different substance use problems.
The place are you able to be taught extra about Dr. Justin Matheson’s work?
Web site: https://www.justinrmatheson.com/
Twitter/X: https://x.com/justinrmatheson
